The MBR-2 became operational in 1933.
A civilian version of the MBR-2 set a record by climbing to 30,000' without cargo in May 1937. This record stood for 23 years.
The Soviet Union and Finland used the MBR-2 during World War II. Finland had captured five MBR-2s in 1941.
The MBR-2's primary role was for coastal reconnaissance. They were mostly stationed with the Soviet Northern and Black Sea fleets.